Channelopathies of Cardiac Inwardly Rectifying Potassium Channels

Andre Terzic; Michel Vivaudou; Christophe Moreau; Timothy M. Olson; Arshad Jahangir; Leonid V. Zingman; Alexey E. Alekseev

doi:10.1007/978-1-84628-854-8_13

Book chapter

Channelopathies of Cardiac Inwardly Rectifying Potassium Channels

Andre Terzic, Michel Vivaudou, Christophe Moreau, Timothy M. Olson, Arshad Jahangir, Leonid V. Zingman and Alexey E. Alekseev

Electrical Diseases of the Heart, pp.207-217

Springer London

2008

DOI: 10.1007/978-1-84628-854-8_13

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Abstract

Diseases resulting from impaired ion channel function—channelopathies—are increasingly recognized pathologies in human cardiovascular medicine.1 Understanding the molecular basis of an ion channel disease has provided new opportunities for screening, early diagnosis, and therapy of these commonly life-threatening conditions. 2, 3 A case in point is the identification of molecular genetic defects in inwardly rectifying potassium (Kir, KCNJ) channels.

Dilate Cardiomyopathy

Hyperinsulinemic Hypoglycemia

KCNJ2 Mutation

Rectify Potassium Channel

Rest Membrane Potential

Details

Title: Subtitle: Channelopathies of Cardiac Inwardly Rectifying Potassium Channels
Creators: Andre Terzic - Mayo Clinic
Michel Vivaudou - Biophysique Moléculaire and Cellulaire CNRS UMR5090 CEA/DRDC
Christophe Moreau - Biophysique Moléculaire and Cellulaire CNRS UMR5090 CEA/DRDC
Timothy M. Olson - Mayo Clinic in Arizona
Arshad Jahangir - Mayo Clinic in Florida
Leonid V. Zingman - Mayo Clinic in Florida
Alexey E. Alekseev - Mayo Clinic
Resource Type: Book chapter
Publication Details: Electrical Diseases of the Heart, pp.207-217
Publisher: Springer London; London
DOI: 10.1007/978-1-84628-854-8_13
Language: English
Date published: 2008
Academic Unit: Internal Medicine
Record Identifier: 9984359951502771

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