Book chapter
Chapter 20 - Translating a treatment for diabetic peripheral neuropathy from rodents to humans: can a case be made for fish oil and salsalate?
Diabetic Neuropathy, pp.337-348
Elsevier Inc
2022
DOI: 10.1016/B978-0-12-820669-0.00006-2
Abstract
According to the American Diabetes Association, in 2015, 9.4% of the United States population had diabetes and statistically, about 50% of these patients will or already have developed peripheral neuropathy. Furthermore, peripheral neuropathy is detectable in about 30% of subjects with prediabetes and impaired glucose tolerance. The only treatment recognized for diabetic peripheral neuropathy (DPN) is glycemic control, which slows progression in patients with type 1 diabetes but is less effective in subjects with type 2 diabetes. With the occurrence of obesity and type 2 diabetes at epidemic levels, there is a critical need of treatment. In this chapter, I will focus on data from my laboratory and others of the potential for omega-3 polyunsaturated fatty acids naturally enriched in fish oil combined with salsalate as a safe and efficacious treatment for DPN.
Details
- Title: Subtitle
- Chapter 20 - Translating a treatment for diabetic peripheral neuropathy from rodents to humans: can a case be made for fish oil and salsalate?
- Creators
- Mark Yorek - University of Iowa
- Resource Type
- Book chapter
- Publication Details
- Diabetic Neuropathy, pp.337-348
- Publisher
- Elsevier Inc
- DOI
- 10.1016/B978-0-12-820669-0.00006-2
- Language
- English
- Date published
- 2022
- Academic Unit
- Fraternal Order of Eagles Diabetes Research Center; Endocrinology and Metabolism; Internal Medicine
- Record Identifier
- 9984359592902771
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