Book chapter
Chapter 48 - Effects of Radiation on Vascular Endothelium
Endothelium and Cardiovascular Diseases, pp.653-663
Academic Press, Second Edition
2026
DOI: 10.1016/B978-0-443-24036-2.00037-3
Abstract
Exposure to ionizing radiation can be expected in different scenarios: medical procedures, occupational exposure, or exposure to environmental sources of ionizing radiation. The expected effects are dependent on the dose and frequency of the exposure. Acute effects of radiation are usually controllable and reversible. However, the most feared are the late effects, which may be permanent and difficult to manage, mainly if severe. Radiation-induced vascular damage plays a key role in the late damage to organs and tissues. However, radiation may also present beneficial effects regarding vascular alterations. Therefore, the clinician should recognize these effects for an appropriate patient management. This chapter will comprise a brief description of the principles of radiobiology and radiotherapy, the physiopathology of radiation damage to the endothelium, radiation-induced cardiovascular diseases, and clinical applications of radiation in vascular disorders.
Details
- Title: Subtitle
- Chapter 48 - Effects of Radiation on Vascular Endothelium
- Creators
- Heloisa de Andrade CarvalhoGeovanne Pedro MauroRosangela Correa Villar
- Resource Type
- Book chapter
- Publication Details
- Endothelium and Cardiovascular Diseases, pp.653-663
- Edition
- Second Edition
- DOI
- 10.1016/B978-0-443-24036-2.00037-3
- Publisher
- Academic Press; Cambridge, MA
- Language
- English
- Date published
- 2026
- Academic Unit
- Radiation Oncology
- Record Identifier
- 9985090735102771
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