Book chapter
Characteristics of Sleep in Critically Ill Patients: Part II: Circadian Rhythm Disruption
Sleep in Critical Illness, pp.15-36
Springer International Publishing
08/31/2022
DOI: 10.1007/978-3-031-06447-0_2
Abstract
Circadian rhythms are ubiquitous in organisms, tuning internal physiology to external conditions and allowing anticipation of environmental daily changes to confer advantage. To synchronize master and peripheral clocks with the environment, organisms entrain their rhythms to external cues. In intensive care units (ICUs), these external cues are mistimed or weak, leading to the desynchronization of patients’ circadian rhythms. This nontherapeutic environment may impair recovery from critical illness. The effects of critical illness itself on circadian rhythms are complex, and it is not known which “dysrhythm” are adaptive and which are harmful and thus represent targets for intervention. In this chapter, we review the basis of circadian rhythms, the circadian disrupters found in ICUs, and the changes in circadian rhythms in critically ill patients.
Details
- Title: Subtitle
- Characteristics of Sleep in Critically Ill Patients: Part II: Circadian Rhythm Disruption
- Creators
- Marie-Anne Melone - University of IowaBrian K. Gehlbach
- Resource Type
- Book chapter
- Publication Details
- Sleep in Critical Illness, pp.15-36
- DOI
- 10.1007/978-3-031-06447-0_2
- Publisher
- Springer International Publishing; Cham
- Language
- English
- Date published
- 08/31/2022
- Academic Unit
- Neurology; Pulmonary, Critical Care, and Occupational Medicine; Health, Sport, and Human Physiology ; Internal Medicine
- Record Identifier
- 9984303555102771
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