Book chapter
Chronic Kidney Disease: A Life Course Health Development Perspective
Handbook of Life Course Health Development, pp.375-401
Springer International Publishing, 1st ed. 2018.
2018
DOI: 10.1007/978-3-319-47143-3_16
Abstract
Chronic kidney disease (CKD) reflects life events that range from maternal-fetal influences to geriatric exposures. The global direct and indirect costs of CKD are high and include maternal-neonatal hospitalization and treatment, acute kidney injury, dialysis and transplant, missed work, and medications, to name a few. The impact of poor diet, adverse childhood experiences, medication use, and failure to follow consistent public health standards are increasingly appreciated as key influences in the development of CKD. Socioeconomic factors can significantly influence the timing and phenotypic expression in people at risk for developing CKD, although more research is needed to understand these mechanisms. In general, biomedicine has been focused on treating well-established CKD morbidity. This strategy has been short sighted and costly. A more cost-effective approach would focus on early life interventions that hold the potential for mitigating CKD risk and its sequelae. This chapter applies the life course health development principles to review determinants and pathways for CKD evolution and identifies of the gaps in our knowledgebase. We also discuss several research strategies for evaluating the life course health development of CKD.
Details
- Title: Subtitle
- Chronic Kidney Disease: A Life Course Health Development Perspective
- Creators
- Patrick D. Brophy - University of Iowa Stead Family Children’s HospitalJennifer R Charlton - University of VirginiaJ. Bryan Carmody - University of VirginiaKimberly J Reidy - Albert Einstein College of MedicineLyndsay A Harshman - University of Iowa, Stead Family Department of PediatricsJeffrey Segar - University of Iowa, Stead Family Department of PediatricsDavid Askenazi - University of Alabama at BirminghamDavid ShohamSusan P Bagby - Oregon Health & Science University
- Resource Type
- Book chapter
- Publication Details
- Handbook of Life Course Health Development, pp.375-401
- Edition
- 1st ed. 2018.
- DOI
- 10.1007/978-3-319-47143-3_16
- Publisher
- Springer International Publishing; Cham
- Number of pages
- 667
- Language
- English
- Date published
- 2018
- Academic Unit
- Nephrology, Dialysis and Transplantation; Stead Family Department of Pediatrics; Iowa Neuroscience Institute
- Record Identifier
- 9984223159002771
Metrics
37 Record Views