Book chapter
Controlled Transport for Pulmonary Drug Delivery
Controlled Pulmonary Drug Delivery, pp.143-163
Advances in Delivery Science and Technology, Springer New York
05/25/2011
DOI: 10.1007/978-1-4419-9745-6_7
Abstract
Interactions between inhaled particles and the respiratory tract fluids are important for inhaled drug delivery systems. In particular, controlling the transport of aerosol particles after deposition in the respiratory tract may improve drug retention time in the lungs, allow targeting, and facilitate optimal transport through innate defense mechanisms of the lung. In this chapter the mechanisms by which particles can transport in the lungs and the aerosol design criteria for improving particle residence times or promoting uniform distribution across or within the lung space are discussed.
Details
- Title: Subtitle
- Controlled Transport for Pulmonary Drug Delivery
- Creators
- Jennifer Fiegel - Department of Pharmaceutical Sciences and Experimental Therapeutics and Department of Chemical and Biochemical Engineering, The University of Iowa, Iowa City, USATimothy BrenzaRania Hamed
- Resource Type
- Book chapter
- Publication Details
- Controlled Pulmonary Drug Delivery, pp.143-163
- Series
- Advances in Delivery Science and Technology
- DOI
- 10.1007/978-1-4419-9745-6_7
- Publisher
- Springer New York; New York, NY
- Language
- English
- Date published
- 05/25/2011
- Academic Unit
- Pharmaceutical Sciences and Experimental Therapeutics; Chemical and Biochemical Engineering
- Record Identifier
- 9984210352502771
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