Diagnosis and Staging of Premalignant and Malignant Diseases of the Liver

Elizabeth Fallon; Frederick Johlin; Alan Stolpen; Jeffrey Dunkelberg

doi:10.1002/9781118555651.ch22

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Book chapter

Diagnosis and Staging of Premalignant and Malignant Diseases of the Liver

Elizabeth Fallon, Frederick Johlin, Alan Stolpen and Jeffrey Dunkelberg

Gastrointestinal Endoscopy in the Cancer Patient, pp.229-241

John Wiley & Sons, Ltd

04/07/2013

DOI: 10.1002/9781118555651.ch22

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Abstract

Premalignant diseases of the liver include chronic hepatitis B, chronic hepatitis C, nonalcoholic steatohepatitis (NASH), cirrhosis from any cause, hepatic adenomas, and primary sclerosing cholangitis (PSC). The primary malignant diseases of the liver are hepatocellular carcinoma (HCC) and cholangiocarcinoma (CCA). HCC occurs most often in cirrhotic patients, especially those with chronic hepatitis B or C. HCC also develops in noncirrhotic patients with hepatitis B or C, NASH, and hepatic adenomas. PSC patients are at risk of CCA. Metastatic liver tumors are the most common malignant hepatic neoplasms in Western countries. Less common hepatic neoplasms include biliary cystadenocarcinoma and fibrolamellar carcinoma. Imaging studies can usually distinguish malignant hepatic lesions from nonmalignant lesions, making biopsy rarely necessary.

Barcelona Clinic Liver Cancer (BCLC) staging system

biliary cystadenocarcinoma

cholangiocarcinoma

cirrhosis

ERCP

fibrolamellar carcinoma

hepatic adenoma

hepatitis B

hepatitis C

hepatocellular carcinoma

intraductal endoscopic ultrasound

intrahepatic cholangiocarcinoma

liver metastases

primary sclerosing cholangitis

Details

Title: Subtitle: Diagnosis and Staging of Premalignant and Malignant Diseases of the Liver
Creators: Elizabeth Fallon
Frederick Johlin
Alan Stolpen
Jeffrey Dunkelberg
Contributors: John C Deutsch (Editor) - Essentia Health Systems Duluth, MN, USA
Matthew R Banks (Editor) - University College London
Resource Type: Book chapter
Publication Details: Gastrointestinal Endoscopy in the Cancer Patient, pp.229-241
DOI: 10.1002/9781118555651.ch22
Publisher: John Wiley & Sons, Ltd; Oxford, UK
Number of pages: 12
Language: English
Date published: 04/07/2013
Academic Unit: Radiology; Gastroenterology and Hepatology; Internal Medicine
Record Identifier: 9984318821202771

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