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Dynamic Volumetric Imaging-Based Assessment of the Intrathoracic Milieu
Book chapter

Dynamic Volumetric Imaging-Based Assessment of the Intrathoracic Milieu

Eric A Hoffman and Binh Q Tran
Respiratory-Circulatory Interactions in Health and Disease, pp.312-347
CRC Press
2001
DOI: 10.1201/b14017-15

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Abstract

The effect of breathing on cardiac performance has long been suspected. As early as 1853, Donders (1) made observations that spontaneous inspiration has the dual effect of increasing the return of venous blood to the heart while decreasing the ejection of blood into the systemic circulation. Since Donders, many others have investigated the effects of breathing on right and left heart dynamics. Most studies have required invasive surgical techniques to open the chest and insert instrumentation (i.e., ultrasonic flowmeters, pressure-tip or liquid-filled catheters, implanted metallic markers) (2-4) to facilitate measurement of hemodynamic and cardiac dimensional changes in response to various breathing protocols. Similarly difficult instrumentation challenges have been faced by those studies interested in evaluating the role of the intrathoracic environment on pulmonary function. Because of the complex interplay between the heart and lungs within the thorax, these invasive procedures most certainly alter the normal interaction between the two physiologic systems.

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