Early-Stage Breast Cancer

Katherine R. Amarell; Kailin Yang; Rahul D. Tendulkar; Chirag Shah

doi:10.1891/9780826191991.0024

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Book chapter

Early-Stage Breast Cancer

Katherine R. Amarell, Kailin Yang, Rahul D. Tendulkar and Chirag Shah

Essentials of Clinical Radiation Oncology, pp.215-238

Demos Medical, Third edition

2026

DOI: 10.1891/9780826191991.0024

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Abstract

Worldwide, breast cancer is the most frequently diagnosed and leading cause of cancer death in women. Breast carcinomas arise from epithelial elements and comprise a diverse group of lesions with differing biological behavior, although often discussed as a single disease with similar management guidelines. Supplemental screening may be necessary in women with genetic predisposition to disease and/or dense breasts. Forty percent of breast lesions are detected by mammogram only, but 10% have palpable tumors that are not visualized. For early-stage breast cancer, treatment typically involves surgical resection followed by adjuvant therapy (chemotherapy, RT, and/or endocrine therapy) depending on pathologic features.

Breast Cancer

Chemotherapy

Endocrine therapy

Mammogram

Radiation therapy

Supplemental screening

Surgical resection

Details

Title: Subtitle: Early-Stage Breast Cancer
Creators: Katherine R. Amarell - Cleveland Clinic
Kailin Yang - Cleveland Clinic
Rahul D. Tendulkar - Cleveland Clinic
Chirag Shah - Allegheny Health Network
Resource Type: Book chapter
Publication Details: Essentials of Clinical Radiation Oncology, pp.215-238
Edition: Third edition
DOI: 10.1891/9780826191991.0024
Publisher: Demos Medical; Princeton, NJ
Language: English
Date published: 2026
Academic Unit: Radiation Oncology
Record Identifier: 9985214914302771

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