Book chapter
Epidemiology of Specific Language Impairment
THE INHERITANCE AND INNATENESS OF GRAMMARS, Gopnik, Myrna [Ed], New York: Oxford U Press, 1997, pp 91-110
01/01/1997
Abstract
Preliminary results are reported from an ongoing epidemiological study of specific language impairment involving direct testing of all first-degree kin of affected individuals; where a parent is found to be affected also, extended kin are tested. Results to date (N = 245 in 42 families) indicate that the risk of specific language impairment in first-degree kin of specific language impairment patients is more than 700% higher than in the general population. Mono- & dizygotic twin studies are cited that suggest that the concordance rate for specific language impairment is closely parallel to the rate of shared genes. Methods of pedigree analysis are explored in this connection, & three hypothetical models of genetic transmission of specific language impairment are outlined. These findings identify familiality & maleness as risk factors for specific language impairment & suggest that a genetic mechanism underlying the familiality factor interacts with biological aspects of maleness to predispose for specific language impairment. 2 Tables, 3 Figures, 46 References. J. Hitchcock
Details
- Title: Subtitle
- Epidemiology of Specific Language Impairment
- Creators
- J Bruce Tomblin
- Resource Type
- Book chapter
- Publication Details
- THE INHERITANCE AND INNATENESS OF GRAMMARS, Gopnik, Myrna [Ed], New York: Oxford U Press, 1997, pp 91-110
- Language
- English
- Date published
- 01/01/1997
- Academic Unit
- Iowa Neuroscience Institute; Communication Sciences and Disorders
- Record Identifier
- 9984071961102771
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