Gene transfer after subarachnoid hemorrhage: a tool and potential therapy

D D Heistad; Y Watanabe; Y Chu

doi:10.1007/978-3-211-75718-5_30

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Gene transfer after subarachnoid hemorrhage: a tool and potential therapy

Book chapter

Peer reviewed

Gene transfer after subarachnoid hemorrhage: a tool and potential therapy

D D Heistad, Y Watanabe and Y Chu

Cerebral Vasospasm, Vol.104(104), pp.157-159

Acta neurochirurgica. Supplement, 104

2008

DOI: 10.1007/978-3-211-75718-5_30

PMID: 18457000

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Abstract

This mini-review describes steps towards gene therapy to prevent vasospasm after subarachnoid hemorrhage, and summarizes some remaining obstacles. With recombinant adenoviruses, it is now possible to prevent vasospasm in experimental animals. If an adenoviral or other effective vector is demonstrated to be safe, it is likely that gene therapy will be used in patients to prevent vasospasm.

Vasospasm, Intracranial - prevention & control

Gene Transfer, Horizontal

Subarachnoid Hemorrhage - genetics

Vasospasm, Intracranial - genetics

Humans

Gene Expression Regulation

Details

Title: Subtitle: Gene transfer after subarachnoid hemorrhage: a tool and potential therapy
Creators: D D Heistad - Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA 52242-1081, USA. donald-heistad@uiowa.edu
Y Watanabe
Y Chu
Resource Type: Book chapter
Publication Details: Cerebral Vasospasm, Vol.104(104), pp.157-159
Publisher: Austria
Series: Acta neurochirurgica. Supplement; 104
DOI: 10.1007/978-3-211-75718-5_30
PMID: 18457000
eISBN: 9783211757185; 321175718X
ISSN: 0065-1419
eISSN: 2197-8395
Grant note: DK 54759 / NIDDK NIH HHS HL 62984 / NHLBI NIH HHS HL 16066 / NHLBI NIH HHS NS 24621 / NINDS NIH HHS P30 DK054759 / NIDDK NIH HHS HL 14388 / NHLBI NIH HHS
Language: English
Date published: 2008
Academic Unit: Cardiovascular Medicine; Neuroscience and Pharmacology; Internal Medicine
Record Identifier: 9984040551002771

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