Book chapter
Immunosuppressive Management of Cardiac Sarcoidosis
Cardiac Sarcoidosis, pp.103-112
Springer International Publishing
02/07/2015
DOI: 10.1007/978-3-319-14624-9_11
Abstract
Sarcoidosis is a multi-system granulomatous disorder of yet unknown etiology that predominantly involves the lungs in over 90 % of cases but can also involve any organ in the body. Cardiac sarcoidosis is detected clinically in about 5 % of patients with sarcoidosis but on autopsy in as many as 40 % suggesting that the majority of cases may be underdiagnosed. Complications of cardiac sarcoidosis can include ventricular dysfunction, conduction abnormalities, ventricular arrhythmias and sudden cardiac death. These may occur suddenly, without warning in a previously asymptomatic or undiagnosed patient. There are currently no guidelines on how to definitively manage cardiac sarcoidosis. The goal of immunosuppressive (IS) therapy in cardiac sarcoidosis is to reverse any ongoing active granulomatous myocarditis, potentially prevent progression of myocardial granulomatous inflammation to scar tissue, and reduce or prevent the development of serious or life threatening cardiac complications. Management of cardiac sarcoidosis requires the collaborative effort of a sarcoidosis expert, an electrophysiologist, and a general cardiologist.
Details
- Title: Subtitle
- Immunosuppressive Management of Cardiac Sarcoidosis
- Creators
- Divya Patel - University of Colorado HospitalNabeel Y. Hamzeh - National Jewish Health
- Resource Type
- Book chapter
- Publication Details
- Cardiac Sarcoidosis, pp.103-112
- Publisher
- Springer International Publishing; Cham
- DOI
- 10.1007/978-3-319-14624-9_11
- Language
- English
- Date published
- 02/07/2015
- Academic Unit
- Pulmonary, Critical Care, and Occupational Medicine; Internal Medicine
- Record Identifier
- 9984359914302771
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