Book chapter
Integrative mechanisms and the maintenance of cardiovascular and body fluid homeostasis: the central processing of sensory input derived from the circumventricular organs of the lamina terminalis
Circumventricular Organs and Brain Fluid Environment: Molecular and Functional Aspects, pp.381-393
Progress in brain research, v. 91, Elsevier
1992
DOI: 10.1016/S0079-6123(08)62357-2
PMID: 1410424
Abstract
This paper discusses the neural substrates and mechanisms involved in the integration and processing of the humorally derived information from two of these sensory circumventricular organs (CVOs), the subfornical organ (SFO) and the organum vasculosum laminae terminalis (OVLT). The CVOs associated with the lamina terminalis, the SFO, and the OVLT in all probability contain sensory elements critical for the maintenance of cardiovascular and body fluid homeostasis. Both anatomical and functional evidence indicates that the SFO and OVLT are reciprocally tied to components of the anteroventral third ventricle (AV3V), particularly the median preoptic nucleus (MnPO). It is reasonable to believe that substantial processing of central input, derived through the two-lamina terminalis-associated CVOs, occurs within the AV3V. The research reviewed in this chapter indicates that the SFO/AV3V is related to mechanisms that maintain consistency in extracellular fluid volume. Specifically, present evidence suggests that ANG II and norepinephrine interact in structures within the AV3V, particularly the ventral MnPO, to facilitate volume expansion. © 1992, Elsevier Science Publishers, B.V.
Details
- Title: Subtitle
- Integrative mechanisms and the maintenance of cardiovascular and body fluid homeostasis: the central processing of sensory input derived from the circumventricular organs of the lamina terminalis
- Creators
- Alan Kim Johnson - Department of Psychology, University of Iowa, Iowa City 52242Andrea M Zardetto-SmithGaylen L Edwards
- Resource Type
- Book chapter
- Publication Details
- Circumventricular Organs and Brain Fluid Environment: Molecular and Functional Aspects, pp.381-393
- Publisher
- Elsevier; Amsterdam
- Series
- Progress in brain research; v. 91
- DOI
- 10.1016/S0079-6123(08)62357-2
- PMID
- 1410424
- ISSN
- 0079-6123
- eISSN
- 1875-7855
- Grant note
- HL 14388 / NHLBI NIH HHS HL 44546 / NHLBI NIH HHS HL 33447 / NHLBI NIH HHS
- Language
- English
- Date published
- 1992
- Academic Unit
- Psychological and Brain Sciences; Neuroscience and Pharmacology; Health and Human Physiology
- Record Identifier
- 9984213419502771
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