Book chapter
Jejunoileal Neuroendocrine Tumors
Neuroendocrine Tumors, pp.157-177
Springer International Publishing
01/05/2021
DOI: 10.1007/978-3-030-62241-1_10
Abstract
Jejunoileal or small bowel neuroendocrine tumors (SBNETs), as with neuroendocrine tumors arising from other anatomic locations, are increasing in incidence. Given the small intestine’s relative inaccessibility to endoscopy and the fact that SBNETs are frequently small, they often elude preoperative identification. Nodal and liver metastases are common at the time of diagnosis. The majority of SBNETs are low grade with slow growth, and with optimal treatment patients can survive for many years, even with metastatic disease. Definitive management includes surgery to remove the primary tumor, associated nodal tissue, and distant metastases, when feasible. For unresectable or recurrent disease, an ever-increasing range of medical therapies including somatostatin analogues, peptide receptor radionuclide therapy, and targeted molecular inhibitors can delay progression and potentially extend survival.
Details
- Title: Subtitle
- Jejunoileal Neuroendocrine Tumors
- Creators
- Scott K. Sherman - Roy J. and Lucille A. Carver College of MedicineJames R. Howe - Roy J. and Lucille A. Carver College of Medicine
- Resource Type
- Book chapter
- Publication Details
- Neuroendocrine Tumors, pp.157-177
- Publisher
- Springer International Publishing; Cham
- DOI
- 10.1007/978-3-030-62241-1_10
- Language
- English
- Date published
- 01/05/2021
- Academic Unit
- Surgery
- Record Identifier
- 9984322774302771
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