Book chapter
Lipid Storage Diseases
Non-Neoplastic Hematologic Disorders, pp.639-656
Springer Nature Switzerland
2024
DOI: 10.1007/978-3-031-62373-8_47
Abstract
Lipid storage diseases are a diverse group of more than 70 rare, distinct disease conditions with the common characteristic of the buildup of metabolic precursors in lysosomes. Intracellular lysosomes are responsible for the degradation of a variety of biomolecules, with several pathways involved. Deficiencies of one of these pathways will lead to accumulation of a substrate and subsequent cellular dysfunction. Various hematologic abnormalities across this spectrum of diseases have been described.
Details
- Title: Subtitle
- Lipid Storage Diseases
- Creators
- Olga Sazanova - University of IowaBrian D. Schlick - Moffitt Cancer CenterLugen Chen - Tampa General HospitalPrerna Rastogi - University of Iowa
- Contributors
- Lubomir Sokol (Editor)Ling Zhang (Editor)
- Resource Type
- Book chapter
- Publication Details
- Non-Neoplastic Hematologic Disorders, pp.639-656
- Publisher
- Springer Nature Switzerland; Cham
- DOI
- 10.1007/978-3-031-62373-8_47
- Language
- English
- Date published
- 2024
- Academic Unit
- Pathology
- Record Identifier
- 9984745355802771
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