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Malignant Solitary Fibrous Tumor of the Pleura Associated with a Paraneoplastic Hypoglycemia
Book chapter

Malignant Solitary Fibrous Tumor of the Pleura Associated with a Paraneoplastic Hypoglycemia

Evgeny V Arshava, Adnan Al Ayoubi and Kalpaj R Parekh
Thoracic Surgery, pp.47-53
CRC Press, 1
2020
DOI: 10.1201/9781315265889-9

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Abstract

Pleural solitary fibrous tumors (SFTs) are uncommon neoplasms that may present late, reaching large sizes. SFTs can be malignant and may be associated with paraneoplastic syndromes. Malignant solitary fibrous tumors (MSFTs) are very uncommon. We describe a rare case of a pleural malignant SFT (MSFTs), presenting with a paraneoplastic hypoglycemia as an initial symptom and normal levels of insulin-like growth factors 1 and 2. Imaging and percutaneous cord- needle biopsy can provide initial diagnosis of an SFT. En-bloc surgical resection with clear margins is a mainstem of treatment. Tumors with malignant potential tend to recur and require long-term surveillance with imaging and repeated resection when feasible, as no reliable adjuvant therapy exists.
Submesothelial Fibromas Core Needle Biopsy Fibrous Mesotheliomas Trachea Esophageal Fistula CT Scan Chest Wall Endoscopic Closure SFTs Fine Needle Aspiration Thymic Epithelial Neoplasm Sarcomatoid Mesothelioma Paraesophageal Hernia Peripheral Nerve Sheath Tumors White Blood Cell High Mitotic Rate Chest Wall Resection Chest Wall Reconstruction Total IGF Fibrous Pseudocapsule Progression Free Survival

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