Book chapter
Mechanisms of Development - 2
Clinical Neuroembryology
Springer International Publishing
01/01/2023
DOI: 10.1007/978-3-031-26098-8_2
Abstract
Many of the mechanisms underlying neural development are basically similar in vertebrates and invertebrates. Among vertebrates, popular species for experimental studies are zebrafish, the South African clawed toad, the chick embryo and mice. In mice, many spontaneously occurring mutations affecting the cerebral cortex and the cerebellum have been described. Their molecular analysis, combined with transgenic technology to achieve ectopic gene expression and targeted gene ablation, has made the mouse the mammal of choice for molecular genetic studies of early development.
Details
- Title: Subtitle
- Mechanisms of Development - 2
- Creators
- Hans J ten DonkelaarBernd Fritzsch - University of Iowa
- Resource Type
- Book chapter
- Publication Details
- Clinical Neuroembryology
- DOI
- 10.1007/978-3-031-26098-8_2
- Publisher
- Springer International Publishing; Cham
- Language
- English
- Date published
- 01/01/2023
- Academic Unit
- Iowa Neuroscience Institute; Biology; Craniofacial Anomalies Research Center
- Record Identifier
- 9984503058302771
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