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Mechanisms of Filovirus Entry
Book chapter   Peer reviewed

Mechanisms of Filovirus Entry

R A Davey, O Shtanko, M Anantpadma, Y Sakurai, K Chandran and W Maury
Marburg- and Ebolaviruses, pp.323-352
Current topics in microbiology and immunology, 411, Springer Cham
2017
DOI: 10.1007/82_2017_14
PMID: 28601947

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Abstract

Filovirus entry into cells is complex, perhaps as complex as any viral entry mechanism identified to date. However, over the past 10 years, the important events required for filoviruses to enter into the endosomal compartment and fuse with vesicular membranes have been elucidated (Fig. 1). Here, we highlight the important steps that are required for productive entry of filoviruses into mammalian cells.

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