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Membranoproliferative glomerulonephritis
Book chapter

Membranoproliferative glomerulonephritis

Carla M Nester and Danniele G Holanda
Clinical Pediatric Nephrology
CRC Press, 3rd edition
11/16/2016
DOI: 10.1201/9781315382319

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Abstract

As advances are made in our understanding of the mechanistic underpinnings of membranoproliferative glomerulonephritis (MGPN), the classication and nomenclature of MPGN as a clinicopathologic entity is being revisited. Children with MPGN may present with nephritic syndrome, nephrotic syndrome, asymptomatic proteinuria, or a nephritic-nephrotic clinical picture. Despite an increased understanding of its pathogenesis, optimal treatment of MPGN remains uncertain.

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