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Molecular genetics of pyrogenic exotoxin "superantigens" of group A streptococci and Staphylococcus aureus
Book chapter   Peer reviewed

Molecular genetics of pyrogenic exotoxin "superantigens" of group A streptococci and Staphylococcus aureus

P K Lee and P M Schlievert
Superantigens , pp.1-19
Current topics in microbiology and immunology, 174, Springer
1991
DOI: 10.1007/978-3-642-50998-8_1
PMID: 1802616

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Abstract

Many bacteria require a complex set of host-parasite interactions in order to cause disease. Perhaps the most straightforward of these interactions is elaboration by the microbe of toxins which induce disease manifestations. In this example the pathogen must only be able to survive and multiply within the host for a sufficient period of time to make the toxin. Toxin-host cell receptor interactions then determine the extent of host tissue damage.
Staphylococcus aureus - genetics Amino Acid Sequence Streptococcus pyogenes - immunology Exotoxins - immunology Molecular Sequence Data Shock, Septic - immunology Antigens, Bacterial - genetics Sequence Homology, Nucleic Acid Streptococcus pyogenes - genetics Enterotoxins - genetics Enterotoxins - immunology Bacterial Toxins Superantigens Exotoxins - genetics Staphylococcus aureus - immunology Gene Expression Regulation, Bacterial

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