Book chapter
Neural Crest: Clinical Features, Human Genetics and Molecular Pathways
Congenital Heart Diseases: The Broken Heart, pp.41-53
Springer Nature
01/01/2016
DOI: 10.1007/978-3-7091-1883-2_4
Abstract
Cardiac neural crest cells (CNCCs) are a subpopulation of cranial neural crest cells that was first described 30 years ago to be required for cardiac outflow septation. Since then the role of the CNCCs in heart development and congenital heart disease has been explored extensively. This chapter will discuss the contributions of the CNCCs to cardiovascular development, the signaling pathways involved in neural crest development, and some of the human congenital heart diseases attributed to aberrant CNCC development.
Details
- Title: Subtitle
- Neural Crest: Clinical Features, Human Genetics and Molecular Pathways
- Creators
- Bijoy Thattaliyath - Duke UniversityMary Hutson - Duke University
- Contributors
- S Rickert-Sperling (Editor)R G Kelly (Editor)D J Driscoll (Editor)
- Resource Type
- Book chapter
- Publication Details
- Congenital Heart Diseases: The Broken Heart, pp.41-53
- Publisher
- Springer Nature; VIENNA
- DOI
- 10.1007/978-3-7091-1883-2_4
- Number of pages
- 13
- Language
- English
- Date published
- 01/01/2016
- Academic Unit
- Stead Family Department of Pediatrics; Cardiology
- Record Identifier
- 9984354118102771
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