Book chapter
Neurodevelopment in Chronic Kidney Disease - 57
Pediatric Kidney Disease, pp.1553-1576
Springer International Publishing, Third edition
01/01/2023
DOI: 10.1007/978-3-031-11665-0_57
Abstract
Pediatric chronic kidney disease (CKD) impacts neurocognitive development, including motor and cognitive function, intelligence (IQ), attention, memory, and academic achievement. This chapter provides a comprehensive overview of data evaluating the effects of mild to moderate pediatric CKD, dialysis, and kidney transplantation on cognitive function and development. The age of onset of CKD and the presence of CKD-associated comorbidities are perhaps the most important determinants of developmental outcome. Performance on IQ testing usually places children with CKD within the broad range of average intelligence but with a skew toward the lower end of a normal distribution and with lower performance than siblings. Executive function, memory and attention deficits are also known to occur in the pediatric CKD population. Relevant literature on neurodevelopment in genetic forms of kidney disease, neuroimaging, and the impact of more frequent hemodialysis are reviewed. Long-term educational and vocational outcomes for children diagnosed with CKD are presented, and recommendations for promoting optimal neurodevelopment and academic achievement are discussed.
Details
- Title: Subtitle
- Neurodevelopment in Chronic Kidney Disease - 57
- Creators
- Rebecca J Johnson - University of Missouri–Kansas CityLyndsay A Harshman
- Resource Type
- Book chapter
- Publication Details
- Pediatric Kidney Disease, pp.1553-1576
- Edition
- Third edition
- Publisher
- Springer International Publishing
- DOI
- 10.1007/978-3-031-11665-0_57
- Language
- English
- Date published
- 01/01/2023
- Academic Unit
- Iowa Neuroscience Institute; Radiation Oncology; Stead Family Department of Pediatrics; Nephrology, Dialysis and Transplantation
- Record Identifier
- 9984406605502771
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