Book chapter
Neurohumoral Regulation of Blood Pressure in Early Development
Pediatric Hypertension, pp.3-21
Clinical Hypertension and Vascular Diseases, Humana Press
2004
DOI: 10.1007/978-1-59259-797-0_1
Abstract
Circulatory function is mediated through interacting neural, hormonal, and metabolic mechanisms acting at both central and local levels. The central nervous system (CNS) in particular is critical for cardiovascular homeostasis (1,2). Autonomic tone to the heart and vasculature is continuously modulated by an array of peripheral sensors, including arterial baroreceptors and chemoreceptors (3). Brain cardiovascular centers located between afferent and efferent pathways of the reflex arc integrate a variety of visceral and behavioral sensations, allowing for a wide range of modulation of specific autonomic, cardiovascular, and endocrine responses. Although these basic mechanisms exist in the fetus and newborn, different rates of maturation of these systems influence the ability of the developing animal to maintain blood pressure (BP) and organ blood flow.
Details
- Title: Subtitle
- Neurohumoral Regulation of Blood Pressure in Early Development
- Creators
- Jeffrey L. SegarJean E. Robillard
- Contributors
- Ronald J. Portman (Editor)Jonathan M. Sorof (Editor)Julie R. Ingelfinger (Editor)
- Resource Type
- Book chapter
- Publication Details
- Pediatric Hypertension, pp.3-21
- Publisher
- Humana Press; Totowa, NJ
- Series
- Clinical Hypertension and Vascular Diseases
- DOI
- 10.1007/978-1-59259-797-0_1
- Language
- English
- Date published
- 2004
- Academic Unit
- Molecular Physiology and Biophysics; Nephrology, Dialysis and Transplantation; Medicine Administration; Stead Family Department of Pediatrics
- Record Identifier
- 9984774209402771
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