Book chapter
Optimization of Radiotherapy Using Biological Parameters
Radiation Oncology Advances, pp.253-274
Cancer Treatment and Research, Springer US
2008
DOI: 10.1007/978-0-387-36744-6_12
PMID: 18236720
Abstract
Most early stage cancers can be cured with either radiotherapy or surgery; however, tumor control for many locally advanced tumors has been unsatisfactory in spite of combined-modality treatments. It has been observed that local recurrence of tumors happens in high-risk tumor subvolumes such as hypoxic tumor subvolumes [1, 2] or regions that contain a large number of highly proliferation-capable clonogens [2, 3]. In an effort to overcome local recurrence, radiation dose boosting techniques have been widely studied. Clinical evidence exists that tumor control can be enhanced using boosting techniques for the following disease sites: head-and-neck (H & N) cancer [4–6], prostate cancer [7, 8], lung cancer [9–11], and liver cancer [12, 13].
Details
- Title: Subtitle
- Optimization of Radiotherapy Using Biological Parameters
- Creators
- Yusung Kim - University of Wisconsin–MadisonWolfgang A. Tomé - University of Wisconsin–Madison
- Resource Type
- Book chapter
- Publication Details
- Radiation Oncology Advances, pp.253-274
- Publisher
- Springer US; Boston, MA
- Series
- Cancer Treatment and Research
- DOI
- 10.1007/978-0-387-36744-6_12
- PMID
- 18236720
- ISSN
- 0927-3042
- Language
- English
- Date published
- 2008
- Academic Unit
- Radiation Oncology
- Record Identifier
- 9984312990002771
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