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Oxidative stress and the vulnerable plaque
Book chapter

Oxidative stress and the vulnerable plaque

Donald Heistad and Yi Chu
Handbook of the Vulnerable Plaque, pp.89-96
CRC Press, Second edition
2006
DOI: 10.3109/9781439804537-12

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Abstract

An extremely hot topic in vascular biology is the role of superoxide and other reactive oxygen species (ROS) in cell signaling and in pathophysiology of vascular disease. The role of ROS in the vulnerable plaque has received remarkably little attention, but may be central to understanding development and rupture of the vulnerable plaque.1

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