Book chapter
Personalized Medicine Approaches to the Prevention, Diagnosis, and Treatment of Chronic Periodontitis
Personalized Oral Health Care, pp.99-112
Springer International Publishing
01/23/2016
DOI: 10.1007/978-3-319-23297-3_8
Abstract
Over the years, the multifactorial and interactive nature of periodontal disease challenged clinicians in an attempt to delineate a pattern for its destructive progression. Periodontal disease is caused by persistent inflammation of the periodontium in response to the colonization of microbes upon the tooth surface near the gingival margin and a subsequent biofilm formation resulting in irreversible attachment loss of marginal alveolar bone and associated periodontal ligament and migration of the junctional epithelium. In spite of the infectious nature of periodontal disease, identification of the oral microbiome and a complete understanding of its pathogenic pathway seem the most logical step toward the development of newer and effective approaches for periodontal therapy.
Details
- Title: Subtitle
- Personalized Medicine Approaches to the Prevention, Diagnosis, and Treatment of Chronic Periodontitis
- Creators
- Carlos Garaicoa-Pazmino - University of Michigan–Ann ArborAnn M. Decker - University of Michigan–Ann ArborPeter J. Polverini - University of Michigan–Ann Arbor
- Resource Type
- Book chapter
- Publication Details
- Personalized Oral Health Care, pp.99-112
- Publisher
- Springer International Publishing; Cham
- DOI
- 10.1007/978-3-319-23297-3_8
- Language
- English
- Date published
- 01/23/2016
- Academic Unit
- Periodontics
- Record Identifier
- 9984367624302771
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