Platelet Rich Plasma: Biology and Clinical Usage in Orthopedics

Dukens LaBaze; Hongshuai Li

doi:10.1007/978-3-319-89542-0_12

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Book chapter

Platelet Rich Plasma: Biology and Clinical Usage in Orthopedics

Dukens LaBaze and Hongshuai Li

Orthopedic Biomaterials, pp.243-286

Springer International Publishing

08/18/2018

DOI: 10.1007/978-3-319-89542-0_12

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Abstract

Biological research in the areas of skeletal, cartilaginous, tendinous, and muscular tissues has led to the advancement of various products designed to augment healing. Platelet-rich plasma (PRP) has been in clinical use and researched since the 1970s because of its regenerative properties. In this chapter, we will first define PRP and its components and discuss various methods of preparation and isolation. The second section will focus on the clinical applications of PRP on tissue specific pathologies including tendinopathy, ligamentous injuries, osteoarthritis, and muscle injuries in the field of orthopedic surgery and sports medicine. Lastly, the latest progress in PRP research will be briefly listed and some promising future directions will be discussed.

Cartilage

Cell differentiation

Cell proliferation

Fibrosis

Growth factor

Ligament

Muscle

Orthopedics surgery

Osteoarthritis

Platelet

Platelet rich plasma

Sports medicine

Tendinopathy

Tendon

Details

Title: Subtitle: Platelet Rich Plasma: Biology and Clinical Usage in Orthopedics
Creators: Dukens LaBaze - University of Pittsburgh
Hongshuai Li - University of Pittsburgh
Resource Type: Book chapter
Publication Details: Orthopedic Biomaterials, pp.243-286
DOI: 10.1007/978-3-319-89542-0_12
Publisher: Springer International Publishing; Cham
Language: English
Date published: 08/18/2018
Academic Unit: Orthopedics and Rehabilitation; Radiation Oncology
Record Identifier: 9984303987302771

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