Book chapter
Recording Extracellular Activity in the Developing Cerebellum of Behaving Rats
Extracellular Recording Approaches, pp.225-247
Neuromethods, Springer New York
12/16/2017
DOI: 10.1007/978-1-4939-7549-5_12
Abstract
The in vivo extracellular activity of the cerebellum has been intensively investigated in adult animals to understand its roles in learning and memory and sensorimotor integration. Here we describe a method for studying extracellular activity in the cerebellum of unanesthetized, behaving infant rodents over the first 2 postnatal weeks, a time of substantial cerebellar circuit development. The study of extracellular activity during cerebellar development in behaving infants provides a unique opportunity to relate neural activity not only to cerebellar circuit development but to behavioral development as well. We propose that studying extracellular neural activity in the developing cerebellum provides a model system for examining the complex interactions between behavior and neural activity and how they contribute together to functional neural circuit development.
Details
- Title: Subtitle
- Recording Extracellular Activity in the Developing Cerebellum of Behaving Rats
- Creators
- Greta Sokoloff - DeLTA Center, University of Iowa, Iowa City, USAMark S Blumberg - Department of Biology, University of Iowa, Iowa City, USA
- Resource Type
- Book chapter
- Publication Details
- Extracellular Recording Approaches, pp.225-247
- Publisher
- Springer New York; New York, NY
- Series
- Neuromethods
- DOI
- 10.1007/978-1-4939-7549-5_12
- eISSN
- 1940-6045
- ISSN
- 0893-2336
- Language
- English
- Date published
- 12/16/2017
- Academic Unit
- Biology; Psychological and Brain Sciences; Iowa Neuroscience Institute
- Record Identifier
- 9984070165202771
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