Book chapter
Role of Dose, Schedule and Route of Administration of 5-Formyltetra-Hydrofolate: Preclinical and Clinical Investigations
The Expanding Role of Folates and Fluoropyrimidines in Cancer Chemotherapy, pp.39-52
Advances in Experimental Medicine and Biology, Springer US
04/01/2012
DOI: 10.1007/978-1-4684-5607-3_4
Abstract
During the last 30 years, 5-fluorouracil (FUra)* has been the drug of choice for treatment of patients with adenocarcinoma of the colon. This agent is also active against breast carcinoma and has significant activity in carcinoma of the head and neck. In all cases, but especially in colon carcinoma, the response rate is low and the duration of response is relatively short, on the order of 6 to 9 months.
Details
- Title: Subtitle
- Role of Dose, Schedule and Route of Administration of 5-Formyltetra-Hydrofolate: Preclinical and Clinical Investigations
- Creators
- Y. M. Rustum - Roswell Park Cancer InstituteL. Liu - Roswell Park Cancer InstituteZ. Zhang - Roswell Park Cancer Institute
- Resource Type
- Book chapter
- Publication Details
- The Expanding Role of Folates and Fluoropyrimidines in Cancer Chemotherapy, pp.39-52
- Publisher
- Springer US; New York, NY
- Series
- Advances in Experimental Medicine and Biology
- DOI
- 10.1007/978-1-4684-5607-3_4
- eISSN
- 2214-8019
- ISSN
- 0065-2598
- Language
- English
- Date published
- 04/01/2012
- Academic Unit
- Hematology, Oncology, and Blood & Marrow Transplantation; Internal Medicine
- Record Identifier
- 9984359786002771
Metrics
21 Record Views