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Skin Diseases Autoantibodies
Book chapter

Skin Diseases Autoantibodies

Luis A. Diaz, Agustin España-Alonso, Janet A. Fairley, George J. Giudice, José M. Mascaró and Zhi Liu
Autoantibodies, pp.746-748
Elsevier Science B.V
1996
DOI: 10.1016/B978-044482383-0/50113-8

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Abstract

This chapter includes autoimmune blistering diseases associated with antidesmosomal and antihemidesmosomal antibodies. Spontaneous blister formation characterizes the acquired autoimmune blistering skin diseases specific for squamous epithelia. Pemphigus foliaceus and pemphigus vulgaris were shown to react with components of the desmosome, an adhesion-related structure associated with the keratinocyte cell surface. The specific autoantibodies and the developments in the immunopathology of these autoimmune diseases of the skin are reviewed.

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