Book chapter
Synthesis of Polychlorinated Biphenyls (PCBs) and Their Metabolites Using the Suzuki-Coupling
PCBs, p.57
The University Press of Kentucky
02/05/2015
Abstract
Polychlorinated biphenyls (PCBs) are industrial chemicals that were used as dielectrics and flame retardants, or in cooling fluids and lubricants. Unfortunately, PCBs have escaped into the environment where they persist and accumulate in animal and human tissues. These characteristics, their propensity to persist and to bioaccumulate, raise concerns about the long-term health effects of these chemicals. They induce various toxic effects like immunosuppression and endocrine disruption in animals and chloracne in humans. PCB mixtures induce liver cancer in rodents (Silberhornet al.1990). In addition, about a dozen epidemiological studies have reported creased mortality due to liver, gall bladder, biliary
Details
- Title: Subtitle
- Synthesis of Polychlorinated Biphenyls (PCBs) and Their Metabolites Using the Suzuki-Coupling
- Creators
- Hans-Joachim LehmlerCarolyn P. BrockBrian PatrickLarry W. Robertson
- Contributors
- Larry Needham (Editor)Heidelore Fiedler (Editor)
- Resource Type
- Book chapter
- Publication Details
- PCBs, p.57
- Publisher
- The University Press of Kentucky
- Language
- English
- Date published
- 02/05/2015
- Academic Unit
- Occupational and Environmental Health; Iowa Neuroscience Institute
- Record Identifier
- 9984000932202771
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