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The Development of Brain Connectivity Supporting Prefrontal Cortical Functions
Book chapter

The Development of Brain Connectivity Supporting Prefrontal Cortical Functions

Silvia A Bunge, Arthur W Toga, Kai Hwang and Beatriz Luna
Principles of Frontal Lobe Function
Oxford University Press
02/01/2013
DOI: 10.1093/med/9780199837755.003.0014

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Abstract

In this chapter, we focus on how brain connectivity develops to support prefrontal cortical functions, with a specific focus on executive control. Anatomical connectivity, functional connectivity, and neural synchrony will be discussed. We will begin by describing developmental changes in white matter integrity as a basis from which to understand agerelated changes in network connectivity. We will then describe what is known about the development of functional networks. Finally, we will discuss what is known regarding agerelated changes in neural synchrony and its implications for mechanisms that may underlie the emergence of network function. Our review will focus on the specialization that occurs from adolescence to adulthood.

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