Book chapter
The Role of T Cell Epitopes in Coronavirus Infection
Experimental Models of Multiple Sclerosis, pp.771-779
Springer
2005
DOI: 10.1007/0-387-25518-4_42
PMCID: PMC7122487
Abstract
Multiple MHV-specific CD4 and CD8 T cell epitopes have been identified in C57Bl/6 and BALB/c mice. In particular, at least two CD8 T cell epitopes are recognized in C57Bl/6 mice. In one model of MHV persistence, mutations are detected in the immunodominant CD8 T cell epitope recognized in this strain. These mutations contribute to virus persistence and to the development of more severe clinical disease.
Details
- Title: Subtitle
- The Role of T Cell Epitopes in Coronavirus Infection
- Creators
- Taeg S Kim - Iowa City, IAStanley Perlman - Iowa City, IA
- Resource Type
- Book chapter
- Publication Details
- Experimental Models of Multiple Sclerosis, pp.771-779
- DOI
- 10.1007/0-387-25518-4_42
- PMCID
- PMC7122487
- eISBN
- 0387255184; 9780387255187
- Publisher
- Springer; Boston, MA
- Language
- English
- Date published
- 2005
- Academic Unit
- Microbiology and Immunology; Stead Family Department of Pediatrics; Iowa Neuroscience Institute; Infectious Disease (Pediatrics)
- Record Identifier
- 9984070454602771
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