Book chapter
Timing, Sleep, and Respiration in Health and Disease
Progress in Molecular Biology and Translational Science, pp.191-219
2013
DOI: 10.1016/B978-0-12-396971-2.00008-7
PMID: 23899599
Abstract
Breathing is perhaps the physiological function that is most vital to human survival. Without breathing and adequate oxygenation of tissues, life ceases. As would be expected for such a vital function, breathing occurs automatically, without the requirement of conscious input. Breathing is subject to regulation by a variety of factors including circadian rhythms and vigilance state. Given the need for breathing to occur continuously with little tolerance for interruption, it is not surprising that breathing is subject to both circadian phase-dependent and vigilance-state-dependent regulation. Similarly, the information regarding respiratory state, including blood−gas concentrations, can affect circadian timing and sleep–wake state. The exact nature of the interactions between breathing, circadian phase, and vigilance state can vary depending upon the species studied and the methodologies employed. These interactions between breathing, circadian phase, and vigilance state may have important implications for a variety of human diseases, including sleep apnea, asthma, sudden unexpected death in epilepsy, and sudden infant death syndrome.
Details
- Title: Subtitle
- Timing, Sleep, and Respiration in Health and Disease
- Creators
- Gordon F Buchanan - Department of Neurology, Yale University School of Medicine, New Haven, Connecticut, USA
- Resource Type
- Book chapter
- Publication Details
- Progress in Molecular Biology and Translational Science, pp.191-219
- DOI
- 10.1016/B978-0-12-396971-2.00008-7
- PMID
- 23899599
- eISSN
- 1878-0814
- ISSN
- 1877-1173
- Language
- English
- Date published
- 2013
- Academic Unit
- Neurology; Iowa Neuroscience Institute
- Record Identifier
- 9984013201002771
Metrics
11 Record Views