Book chapter
Varicella-zoster virus with a lost gE epitope: evidence for immunological pressure by the human antibody response
Immunity to and Prevention of Herpes Zoster, Vol.17, pp.27-39
Archives of virology. Supplementum, 17, Springer
2001
DOI: 10.1007/978-3-7091-6259-0_4
PMID: 11339548
Abstract
The varicella-zoster virus (VZV) genome contains about 70 open reading frames (ORF). ORF 68 codes for glycoprotein gE, formerly called gpl, which is the predominant VZV glycoprotein; gE is a typical type 1 transmembrane protein with 623 amino acids. Recently, a variant virus was discovered which has a mutation in gE codon 150; this mutation converts an aspartic acid into an asparagine residue.
Details
- Title: Subtitle
- Varicella-zoster virus with a lost gE epitope: evidence for immunological pressure by the human antibody response
- Creators
- J A Padilla - Department of Microbiology & Pediatrics, University of Iowa, Iowa City, USAC Grose
- Resource Type
- Book chapter
- Publication Details
- Immunity to and Prevention of Herpes Zoster, Vol.17, pp.27-39
- Publisher
- Springer; Vienna
- Series
- Archives of virology. Supplementum; 17
- DOI
- 10.1007/978-3-7091-6259-0_4
- PMID
- 11339548
- ISSN
- 0939-1983
- Grant note
- AI22795 / NIAID NIH HHS AI36884 / NIAID NIH HHS
- Language
- English
- Date published
- 2001
- Academic Unit
- Stead Family Department of Pediatrics; Infectious Disease (Pediatrics)
- Record Identifier
- 9984093477602771
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