Conference proceeding
3-D segmentation of retinal blood vessels in spectral-domain OCT volumes of the optic nerve head
Proceedings of SPIE, Vol.7626(1), pp.76260V-76260V-8
Medical Imaging 2010: Biomedical Applications in Molecular, Structural, and Functional Imaging
03/09/2010
DOI: 10.1117/12.844330
Abstract
Segmentation of retinal blood vessels can provide important information for detecting and tracking retinal vascular diseases including diabetic retinopathy, arterial hypertension, arteriosclerosis and retinopathy of prematurity (ROP). Many studies on 2-D segmentation of retinal blood vessels from a variety of medical images have been performed. However, 3-D segmentation of retinal blood vessels from spectral-domain optical coherence tomography (OCT) volumes, which is capable of providing geometrically accurate vessel models, to the best of our knowledge, has not been previously studied. The purpose of this study is to develop and evaluate a method that can automatically detect 3-D retinal blood vessels from spectral-domain OCT scans centered on the optic nerve head (ONH). The proposed method utilized a fast multiscale 3-D graph search to segment retinal surfaces as well as a triangular mesh-based 3-D graph search to detect retinal blood vessels. An experiment on 30 ONH-centered OCT scans (15 right eye scans and 15 left eye scans) from 15 subjects was performed, and the mean unsigned error in 3-D of the computer segmentations compared with the independent standard obtained from a retinal specialist was 3.4 ± 2.5 voxels (0.10 ± 0.07 mm).
Details
- Title: Subtitle
- 3-D segmentation of retinal blood vessels in spectral-domain OCT volumes of the optic nerve head
- Creators
- Kyungmoo Lee - The Univ. of Iowa (United States)Michael D Abràmoff - The Univ. of Iowa (United States) and Veterans Administration Medical Ctr., Iowa City (United States)Meindert Niemeijer - Univ. Medical Ctr. Utrecht (Netherlands)Mona K Garvin - The Univ. of Iowa (United States)Milan Sonka - The Univ. of Iowa (United States)
- Resource Type
- Conference proceeding
- Publication Details
- Proceedings of SPIE, Vol.7626(1), pp.76260V-76260V-8
- Conference
- Medical Imaging 2010: Biomedical Applications in Molecular, Structural, and Functional Imaging
- DOI
- 10.1117/12.844330
- ISSN
- 0277-786X
- Language
- English
- Date published
- 03/09/2010
- Academic Unit
- Roy J. Carver Department of Biomedical Engineering; Electrical and Computer Engineering; Radiation Oncology; Injury Prevention Research Center; Ophthalmology and Visual Sciences
- Record Identifier
- 9983806375702771
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