Conference proceeding
Automated 3D region-based volumetric estimation of optic disc swelling in papilledema using spectral-domain optical coherence tomography
Proceedings of SPIE - The International Society for Optical Engineering, Vol.8672, pp.867214-867214-8
03/29/2013
DOI: 10.1117/12.2007001
Abstract
The six-stage Frisén scale is a qualitative and subjective method for assessing papilledema (optic disc swelling due to raised intracranial pressure) using fundus photographs. The recent introduction of spectral-domain optical coherence tomography (SD-OCT) presents a promising alternative to enable the 3-D quantitative estimation of papilledema. In this work, we propose an automated region-based volumetric estimation of the degree of papilledema from SD-OCT. After using a custom graph-based approach to segment the surfaces of the swollen optic nerve head, the volumes of the nasal, superior, temporal, and inferior regions are computed. Using a dataset of 70 SD-OCT optic-nerve-head (ONH) SD-OCT scans the Spearman rank correlation coefficients between expert-defined Frisén scale grades and the total retinal (TR) volume, nasal, superior, temporal, inferior regional volumes were 0.737, 0.752, 0.747, 0.770 and 0.758, respectively. Also, a fuzzy k-nearest-neighbor (k-NN) algorithm was used to predict Frisén scale grades (in a leave-one-subject-out fashion). Using multiple features rather than just the TR volume made the resulting mean Frisén grade difference (MGD) between the expert-defined grades 0.386 (down from 0.629) and prediction accuracy 64.29% (up from 41.43%).
Details
- Title: Subtitle
- Automated 3D region-based volumetric estimation of optic disc swelling in papilledema using spectral-domain optical coherence tomography
- Creators
- Jui-Kai Wang - The Univ. of Iowa (United States)Mohammad Saleh Miri - The Univ. of Iowa (United States)Randy H Kardon - The Univ. of Iowa (United States)Mona K Garvin - The Univ. of Iowa (United States)
- Contributors
- John B Weaver (Editor)Robert C Molthen (Editor)
- Resource Type
- Conference proceeding
- Publication Details
- Proceedings of SPIE - The International Society for Optical Engineering, Vol.8672, pp.867214-867214-8
- DOI
- 10.1117/12.2007001
- ISSN
- 1605-7422
- Publisher
- SPIE
- Language
- English
- Date published
- 03/29/2013
- Academic Unit
- Electrical and Computer Engineering; Iowa Neuroscience Institute; Ophthalmology and Visual Sciences
- Record Identifier
- 9983979938202771
Metrics
31 Record Views