Conference proceeding
Automated segmentation of 3-D spectral OCT retinal blood vessels by neural canal opening false positive suppression
Medical image computing and computer assisted intervention 13th international conference. Part III, Vol.13, pp.33-40
2010
PMID: 20879380
Abstract
We present a method for automatically segmenting the blood vessels in optic nerve head (ONH) centered spectral-domain optical coherence tomography (SD-OCT) volumes, with a focus on the ability to segment the vessels in the region near the neural canal opening (NCO). The algorithm first pre-segments the NCO using a graph-theoretic approach. Oriented Gabor wavelets rotated around the center of the NCO are applied to extract features in a 2-D vessel-aimed projection image. Corresponding oriented NCO-based templates are utilized to help suppress the false positive tendency near the NCO boundary. The vessels are identified in a vessel-aimed projection image using a pixel classification algorithm. Based on the 2-D vessel profiles, 3-D vessel segmentation is performed by a triangular-mesh-based graph search approach in the SD-OCT volume. The segmentation method is trained on 5 and is tested on 10 randomly chosen independent ONH-centered SD-OCT volumes from 15 subjects with glaucoma. Using ROC analysis, for the 2-D vessel segmentation, we demonstrate an improvement over the closest previous work with an area under the curve (AUC) of 0.81 (0.72 for previously reported approach) for the region around the NCO and 0.84 for the region outside the NCO (0.81 for previously reported approach).
Details
- Title: Subtitle
- Automated segmentation of 3-D spectral OCT retinal blood vessels by neural canal opening false positive suppression
- Creators
- Zhihong Hu - Department of Electrical, The University of Iowa, Iowa City, IA, USA. zhihong-hu@uiowa.eduMeindert NiemeijerMichael D Abràmoff - University of Iowa, Ophthalmology and Visual SciencesKyungmoo LeeMona K Garvin
- Resource Type
- Conference proceeding
- Publication Details
- Medical image computing and computer assisted intervention 13th international conference. Part III, Vol.13, pp.33-40
- Publisher
- Springer; Berlin
- PMID
- 20879380
- Language
- English
- Date published
- 2010
- Academic Unit
- Ophthalmology and Visual Sciences; Electrical and Computer Engineering; Roy J. Carver Department of Biomedical Engineering
- Record Identifier
- 9983806372302771
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