Conference proceeding
Automated segmentation of the optic disc margin in 3-D optical coherence tomography images using a graph-theoretic approach
Proceedings of SPIE, Vol.7262(1), pp.72620U-72620U-11
Medical Imaging 2009: Biomedical Applications in Molecular, Structural, and Functional Imaging
02/26/2009
DOI: 10.1117/12.811694
Abstract
The optic disc margin is of interest due to its use for detecting and managing glaucoma. We developed a method for segmenting the optic disc margin of the optic nerve head (ONH) in spectral-domain optical coherence tomography (OCT) images using a graph-theoretic approach. A small number of slices surrounding the Bruch's membrane opening (BMO) plane was taken and used for creating planar 2-D projection images. An edge-based cost function - more specifically, a signed edge-based term favoring a dark-to-bright transition in the vertical direction of polar projection images (corresponding to the radial direction in Cartesian coordinates) - was obtained. Information from the segmented vessels was used to suppress the vasculature influence by modifying the polar cost function and remedy the segmentation difficulty due to the presence of large vessels. The graph search was performed in the modified edge-based cost images. The algorithm was tested on 22 volumetric OCT scans. The segmentation results were compared with expert segmentations on corresponding stereo fundus disc photographs. We found a signed mean difference of 0.0058 ± 0.0706 mm and an unsigned mean difference of 0.1083 ± 0.0350 mm between the automatic and expert segmentations.
Details
- Title: Subtitle
- Automated segmentation of the optic disc margin in 3-D optical coherence tomography images using a graph-theoretic approach
- Creators
- Zhihong Hu - University of IowaMeindert Niemeijer - University of IowaKyungmoo Lee - The Univ. of Iowa (USA)Michael D Abràmoff - The Univ. of Iowa (USA)Milan Sonka - The Univ. of Iowa (USA)Mona K Garvin - The Univ. of Iowa (USA)
- Resource Type
- Conference proceeding
- Publication Details
- Proceedings of SPIE, Vol.7262(1), pp.72620U-72620U-11
- Conference
- Medical Imaging 2009: Biomedical Applications in Molecular, Structural, and Functional Imaging
- DOI
- 10.1117/12.811694
- ISSN
- 0277-786X
- Language
- English
- Date published
- 02/26/2009
- Academic Unit
- Roy J. Carver Department of Biomedical Engineering; Electrical and Computer Engineering; Radiation Oncology; Injury Prevention Research Center; Ophthalmology and Visual Sciences
- Record Identifier
- 9983806283002771
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