Conference proceeding
Biodegradable radiopaque microspheres for the evaluation of regional pulmonary blood flow distribution using electron-beam computed tomography
Proceedings of SPIE, Vol.2168(1), pp.393-405
Medical Imaging 1994: Physiology and Function from Multidimensional Images
05/01/1994
DOI: 10.1117/12.174413
Abstract
Accurate measurement of regional pulmonary blood flow distribution is of interest both as a research and diagnostic tool. Measurements of regional pulmonary perfusion via x-ray CT offer the possibility of detecting perfusion deficits due to pulmonary embolus while maintaining a high degree of anatomic detail. Use of bolus injection of conventional radiopaque contrast with associated short mean transit times (5 - 7 seconds), requires a high degree of temporal resolution offered clinically only by electron beam x-ray CT (Imatron). The present study was intended to characterize biodegradable radiopaque microspheres as an alternative contrast agent which would allow for measurement of regional pulmonary blood flow with scanning times associated with conventional or spiral thin slice, volumetric x-ray CT protocols. To test this, a dog was scanned at 6 slice levels and 13 time points with image acquisition gated to the cardiac cycle. Lung volumes were maintained at functional residual capacity.
Details
- Title: Subtitle
- Biodegradable radiopaque microspheres for the evaluation of regional pulmonary blood flow distribution using electron-beam computed tomography
- Creators
- Michael J Workman - University of IowaJehangir K Tajik - University of IowaMiguel T Robinson - University of IowaEric A Hoffman - University of Iowa
- Resource Type
- Conference proceeding
- Publication Details
- Proceedings of SPIE, Vol.2168(1), pp.393-405
- Conference
- Medical Imaging 1994: Physiology and Function from Multidimensional Images
- DOI
- 10.1117/12.174413
- ISSN
- 0277-786X
- eISSN
- 1996-756X
- Language
- English
- Date published
- 05/01/1994
- Academic Unit
- Internal Medicine; Roy J. Carver Department of Biomedical Engineering; Radiology
- Record Identifier
- 9984318805902771
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