Conference proceeding
Blind source separation in retinal videos
Proceedings of SPIE, Vol.5032(1), pp.1591-1601
Medical Imaging 2003: Image Processing
05/16/2003
DOI: 10.1117/12.481361
Abstract
An optical imaging device of retina function (OID-RF) has been developed to measure changes in blood oxygen saturation due to neural activity resulting from visual stimulation of the photoreceptors in the human retina. The video data that are collected represent a mixture of the functional signal in response to the retinal activation and other signals from undetermined physiological activity. Measured changes in reflectance in response to the visual stimulus are on the order of 0.1% to 1.0% of the total reflected intensity level which makes the functional signal difficult to detect by standard methods since it is masked by the other signals that are present. In this paper, we apply principal component analysis (PCA), blind source separation (BSS), using Extended Spatial Decorrelation (ESD) and independent component analysis (ICA) using the Fast-ICA algorithm to extract the functional signal from the retinal videos. The results revealed that the functional signal in a stimulated retina can be detected through the application of some of these techniques.
Details
- Title: Subtitle
- Blind source separation in retinal videos
- Creators
- Eduardo S Barriga - Univ. of New Mexico (USA)Paul W Truitt - Kestrel Corp. (USA)Marios S Pattichis - Univ. of New Mexico (USA)Dan T'so - SUNY Health Science Ctr. (USA)Young H Kwon - Univ. of Iowa (USA)Randy H Kardon - Univ. of Iowa (USA)Peter Soliz - Kestrel Corp. (USA)
- Resource Type
- Conference proceeding
- Publication Details
- Proceedings of SPIE, Vol.5032(1), pp.1591-1601
- Conference
- Medical Imaging 2003: Image Processing
- DOI
- 10.1117/12.481361
- ISSN
- 0277-786X
- Language
- English
- Date published
- 05/16/2003
- Academic Unit
- Ophthalmology and Visual Sciences; Iowa Neuroscience Institute
- Record Identifier
- 9984070449502771
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