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Clustering for bioinformatics via matrix optimization
Conference proceeding

Clustering for bioinformatics via matrix optimization

Suely Oliveira and David Stewart
Proceedings of the 2nd ACM Conference on bioinformatics, computational biology and biomedicine, pp.559-563
BCB '11
08/01/2011
DOI: 10.1145/2147805.2147900

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Abstract

A new matrix-based clustering method is presented that is able to handle medium to large data sets that is related to semi-definite programming techniques. The method proposed involves solving a non-convex optimization problem. The problem of local minima that are far from global minima, however, does not appear to be a great difficulty. The method was applied to a well known biological clustering problem, and appears to produce consistent clusterings that are close to the original claimed clustering.
clustering optimization semi-definite programming

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