Conference proceeding
Combined use of high-definition and volumetric optical coherence tomography for the segmentation of neural canal opening in cases of optic nerve edema
Progress in Biomedical Optics and Imaging - Proceedings of SPIE, Vol.9413, pp.94133V-94133V-9
03/20/2015
DOI: 10.1117/12.2081485
Abstract
In cases of optic-nerve-head edema, the presence of the swelling reduces the visibility of the underlying neural canal opening (NCO) within spectral-domain optical coherence tomography (SD-OCT) volumes. Consequently, traditional SD-OCT-based NCO segmentation methods often overestimate the size of the NCO. The visibility of the NCO can be improved using high-definition 2D raster scans, but such scans do not provide 3D contextual image information. In this work, we present a semi-automated approach for the segmentation of the NCO in cases of optic disc edema by combining image information from volumetric and high-definition raster SD-OCT image sequences. In particular, for each subject, five high-definition OCT B-scans and the OCT volume are first separately segmented, and then the five high-definition B-scans are automatically registered to the OCT volume. Next, six NCO points are placed (manually, in this work) in the central three high-definition OCT B-scans (two points for each central B-scans) and are automatically transferred into the OCT volume. Utilizing a combination of these mapped points and the 3D image information from the volumetric scans, a graph-based approach is used to identify the complete NCO on the OCT en-face image. The segmented NCO points using the new approach were significantly closer to expert-marked points than the segmented NCO points using a traditional approach (root mean square differences in pixels: 5.34 vs. 21.71, p < 0.001).
Details
- Title: Subtitle
- Combined use of high-definition and volumetric optical coherence tomography for the segmentation of neural canal opening in cases of optic nerve edema
- Creators
- Jui-Kai Wang - The Univ. of Iowa (United States)Randy H Kardon - The Univ. of Iowa (United States)Mona K Garvin - Iowa City VA Health Care System (United States)
- Contributors
- Sébastien Ourselin (Editor) - Univ. College London (United Kingdom)Martin A Styner (Editor) - The Univ. of North Carolina at Chapel Hill (United States)
- Resource Type
- Conference proceeding
- Publication Details
- Progress in Biomedical Optics and Imaging - Proceedings of SPIE, Vol.9413, pp.94133V-94133V-9
- Publisher
- SPIE
- DOI
- 10.1117/12.2081485
- ISSN
- 1605-7422
- Language
- English
- Date published
- 03/20/2015
- Academic Unit
- Electrical and Computer Engineering; Ophthalmology and Visual Sciences; Iowa Neuroscience Institute
- Record Identifier
- 9984070705002771
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