Conference proceeding
Deep LOGISMOS: Deep learning graph-based 3D segmentation of pancreatic tumors on CT scans
2018 IEEE 15th International Symposium on Biomedical Imaging (ISBI 2018), Vol.2018-, pp.1230-1233
04/2018
DOI: 10.1109/ISBI.2018.8363793
Abstract
This paper reports Deep LOGISMOS approach to 3D tumor segmentation by incorporating boundary information derived from deep contextual learning to LOGISMOS - layered optimal graph image segmentation of multiple objects and surfaces. Accurate and reliable tumor segmentation is essential to tumor growth analysis and treatment selection. A fully convolutional network (FCN), UNet, is first trained using three adjacent 2D patches centered at the tumor, providing contextual UNet segmentation and probability map for each 2D patch. The UNet segmentation is then refined by Gaussian Mixture Model (GMM) and morphological operations. The refined UNet segmentation is used to provide the initial shape boundary to build a segmentation graph. The cost for each node of the graph is determined by the UNet probability maps. Finally, a max-flow algorithm is employed to find the globally optimal solution thus obtaining the final segmentation. For evaluation, we applied the method to pancreatic tumor segmentation on a dataset of 51 CT scans, among which 30 scans were used for training and 21 for testing. With Deep LOGISMOS, DICE Similarity Coefficient (DSC) and Relative Volume Difference (RVD) reached 83.2±7.8% and 18.6±17.4% respectively, both are significantly improved (p<;0.05) compared with contextual UNet and/or LOGISMOS alone.
Details
- Title: Subtitle
- Deep LOGISMOS: Deep learning graph-based 3D segmentation of pancreatic tumors on CT scans
- Creators
- Zhihui Guo - Iowa Inst. for Biomed. Imaging, Univ. of Iowa, Iowa City, IA, USALing Zhang - National Institutes of HealthLe Lu - National Institutes of HealthMohammadhadi Bagheri - National Institutes of HealthRonald M Summers - National Institutes of HealthMilan Sonka - University of IowaJianhua Yao - National Institutes of Health
- Resource Type
- Conference proceeding
- Publication Details
- 2018 IEEE 15th International Symposium on Biomedical Imaging (ISBI 2018), Vol.2018-, pp.1230-1233
- DOI
- 10.1109/ISBI.2018.8363793
- ISSN
- 1945-7928
- eISSN
- 1945-8452
- Publisher
- IEEE
- Language
- English
- Date published
- 04/2018
- Academic Unit
- Roy J. Carver Department of Biomedical Engineering; Electrical and Computer Engineering; Radiation Oncology; Fraternal Order of Eagles Diabetes Research Center; Injury Prevention Research Center; Ophthalmology and Visual Sciences
- Record Identifier
- 9984186693602771
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