Conference proceeding
Design of a compact collimator and 3D imaging system for a scanning beam low-energy intraoperative radiation therapy system for pancreatic cancer
2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), Vol.2017, pp.4325-4328
07/2017
DOI: 10.1109/EMBC.2017.8037813
PMID: 29060854
Abstract
Intraoperative radiation therapy (IORT) involves delivering high doses of radiation directly to tumors while sparing healthy tissues in a surgical setting. Current IORT systems are limited in their lack of image guidance and variable needs for shielded operating rooms. They also lack the capability to deliver non-uniform therapeutic radiation to irregular shaped clinical targets. We developed a scanning beam IORT system (SBIORT) to overcome these limitations. SBIORT consists of a low energy x-ray source, a custom compact dynamic x-ray collimator system, a robotic arm, and a 3D surface imaging module. Here we describe the design and validation of the compact dynamic x-ray collimator system and the 3D surface imaging module for use in SBIORT. The proposed collimator can achieve a leaf position accuracy of ± 0.25 mm (95% confidence interval). Phantom studies indicated the 3D surface-imaging module has an accuracy of 1.0 ± 0.6 mm with ability to obtain high resolution surface image within 5 seconds. SBIORT is a novel approach to deliver conformal intensity-modulated intraoperative radiation therapy.
Details
- Title: Subtitle
- Design of a compact collimator and 3D imaging system for a scanning beam low-energy intraoperative radiation therapy system for pancreatic cancer
- Creators
- Brennen Wears - Dept. of Mech. Eng., Univ. of Iowa, Iowa City, IA, USAImran Mohiuddin - Dept. of Radiat. Oncology, Univ. of Iowa, Iowa City, IA, USARyan Flynn - Dept. of Radiat. Oncology, Univ. of Iowa, Iowa City, IA, USAYusung Kim - Dept. of Radiat. Oncology, Univ. of Iowa, Iowa City, IA, USATimothy Waldron - Dept. of Radiat. Oncology, Univ. of Iowa, Iowa City, IA, USABryan Allen - Dept. of Radiat. Oncology, Univ. of Iowa, Iowa City, IA, USAJunyi Xia - Dept. of Radiat. Oncology, Univ. of Iowa, Iowa City, IA, USA
- Resource Type
- Conference proceeding
- Publication Details
- 2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), Vol.2017, pp.4325-4328
- Publisher
- IEEE
- DOI
- 10.1109/EMBC.2017.8037813
- PMID
- 29060854
- ISSN
- 1557-170X
- eISSN
- 2694-0604
- Language
- English
- Date published
- 07/2017
- Academic Unit
- Radiation Oncology
- Record Identifier
- 9984047677502771
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