Conference proceeding
Does sensitivity measured from screening test-sets predict clinical performance?
Progress in Biomedical Optics and Imaging - Proceedings of SPIE, Vol.9037, pp.90370R-90370R-7
03/11/2014
DOI: 10.1117/12.2035111
Abstract
Aim: To examine the relationship between sensitivity measured from the BREAST test-set and clinical performance. Background: Although the UK and Australia national breast screening programs have regarded PERFORMS and BREAST test-set strategies as possible methods of estimating readers' clinical efficacy, the relationship between test-set and real life performance results has never been satisfactorily understood. Methods: Forty-one radiologists from BreastScreen New South Wales participated in this study. Each reader interpreted a BREAST test-set which comprised sixty de-identified mammographic examinations sourced from the BreastScreen Digital Imaging Library. Spearman's rank correlation coefficient was used to compare the sensitivity measured from the BREAST test-set with screen readers' clinical audit data. Results: Results shown statistically significant positive moderate correlations between test-set sensitivity and each of the following metrics: rate of invasive cancer per 10 000 reads (r=0.495; p < 0.01); rate of small invasive cancer per 10 000 reads (r=0.546; p < 0.001); detection rate of all invasive cancers and DCIS per 10 000 reads (r=0.444; p < 0.01). Conclusion: Comparison between sensitivity measured from the BREAST test-set and real life detection rate demonstrated statistically significant positive moderate correlations which validated that such test-set strategies can reflect readers' clinical performance and be used as a quality assurance tool. The strength of correlation demonstrated in this study was higher than previously found by others.
Details
- Title: Subtitle
- Does sensitivity measured from screening test-sets predict clinical performance?
- Creators
- BaoLin P Soh - The Univ. of Sydney (Australia)Warwick B Lee - BreastScreen NSW (Australia)Claudia R Mello-Thoms - The Univ. of Sydney (Australia)Kriscia A Tapia - The Univ. of Sydney (Australia)John Ryan - Ziltron (Ireland)Wai Tak Hung - BreastScreen NSW (Australia)Graham J Thompson - BreastScreen NSW (Australia)Rob Heard - The Univ. of Sydney (Australia)Patrick C Brennan - The Univ. of Sydney (Australia)
- Contributors
- Claudia R Mello-Thoms (Editor) - The Univ. of Sydney (Australia)Matthew A Kupinski (Editor) - College of Optical Sciences, The Univ. of Arizona (United States)
- Resource Type
- Conference proceeding
- Publication Details
- Progress in Biomedical Optics and Imaging - Proceedings of SPIE, Vol.9037, pp.90370R-90370R-7
- Publisher
- SPIE
- DOI
- 10.1117/12.2035111
- ISSN
- 1605-7422
- Language
- English
- Date published
- 03/11/2014
- Academic Unit
- Roy J. Carver Department of Biomedical Engineering; Radiology
- Record Identifier
- 9984051742902771
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