Conference proceeding
Dynamic in vivo Alveolar Morphology Using a Novel Laser Scanning Confocal Microscope
9th Biennial Conference of the Australian Pattern Recognition Society on Digital Image Computing Techniques and Applications (DICTA 2007), pp.99-105
12/2007
DOI: 10.1109/DICTA.2007.4426782
Abstract
Understanding the structure and function of alveoli in vivo is crucial for understanding the normal and diseased lung. In this study we image the alveoli of mice in vivo, using a custom fiber optic catheter based laser scanning confocal microscope. Images obtained using this system are analyzed with an automated software application for alveolar size, wall thickness and alveolar number. Results show that direct dynamic visualization of alveoli and surrounding structures is possible in vivo, with high resolution. Early results indicate a high heterogeneity in alveolar structure in vivo, as opposed to an ordered uniform structure. Using the techniques presented in this study there is great promise for advancing our knowledge of the functional unit of the lung, the alveoli; for alveolar mechanics, cell traffic and 3D structural visualization.
Details
- Title: Subtitle
- Dynamic in vivo Alveolar Morphology Using a Novel Laser Scanning Confocal Microscope
- Creators
- Eman NamatiJacqueline ThiesseJessica de RykGeoffrey McLennan
- Resource Type
- Conference proceeding
- Publication Details
- 9th Biennial Conference of the Australian Pattern Recognition Society on Digital Image Computing Techniques and Applications (DICTA 2007), pp.99-105
- DOI
- 10.1109/DICTA.2007.4426782
- Publisher
- IEEE
- Language
- English
- Date published
- 12/2007
- Academic Unit
- Roy J. Carver Department of Biomedical Engineering; Radiology
- Record Identifier
- 9984318715802771
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