Conference proceeding
Feasibility of using high-speed electron beam x-ray CT (EBCT) to follow the time course of the pulmonary response to pneumonectomy in rabbits
Proceedings of SPIE, Vol.2168(1), pp.341-352
Medical Imaging 1994: Physiology and Function from Multidimensional Images
05/01/1994
DOI: 10.1117/12.174408
Abstract
This report focuses on preliminary experiments designed to determine regional blood flows and air, blood, and tissue contents at end expiratory lung volume in anesthetized, paralyzed, normal, sham-operated, and pneumonectomized (left lung removed) rabbits with and without wax plombage. High temporal resolution measurements were made with an EBCT scanner during the mechanical injection of a bolus of radiopaque contrast material into the pulmonary vasculature. The time-intensity curves of selected lung regions were analyzed with VIDA
using a modification of the myocardial blood flow model proposed by Wolfkiel et al. The resulting data provided an estimate of regional blood flow and total and regional air, blood and `tissue' contents, where `tissue' represents intracellular and interstitial water, i.e., lung water exclusive of blood. The estimates of mean lung air, blood and tissue contents were similar across groups and consistent with anticipated results.
Details
- Title: Subtitle
- Feasibility of using high-speed electron beam x-ray CT (EBCT) to follow the time course of the pulmonary response to pneumonectomy in rabbits
- Creators
- L. E Olson - The Ohio State UniversityV. P Wright - The Ohio State UniversityEric A Hoffman - University of Iowa
- Resource Type
- Conference proceeding
- Publication Details
- Proceedings of SPIE, Vol.2168(1), pp.341-352
- Conference
- Medical Imaging 1994: Physiology and Function from Multidimensional Images
- DOI
- 10.1117/12.174408
- ISSN
- 0277-786X
- Language
- English
- Date published
- 05/01/1994
- Academic Unit
- Roy J. Carver Department of Biomedical Engineering; Radiology; Internal Medicine
- Record Identifier
- 9984318823602771
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