Conference proceeding
In vitro osteoblast responses to cpTi and Ti-6Al-4V alloy
Medical Applications of Titanium and Its Alloys: The Material and Biological Issues, ASTM STP 1272, pp.319-332
01/01/1996
DOI: 10.1520/STP16088S
Abstract
Commercially pure Ti and Ti-6Al-4V have been widely used as dental implant materials. Several reports have demonstrated that there are subtle differences in the nature of the oxide between these two materials which may have important biological consequences. An earlier report by our group demonstrated differences in oxide chemistry between cpTi and Ti alloy does not affect short term in vitro responses of osteoblast cultures. In this work, long term phenotypic expression of typical bone cell markers such as osteocalcin and alkaline phosphatase were not different between metal or control surfaces. There was a slight difference in total Ca super(+2) per culture for alloy compared to cpTi, however, these differences were not statistically different. Based on this work, both cpTi and Ti alloy surfaces support in vitro biological mineralization and are in general agreement with in vivo findings.
Details
- Title: Subtitle
- In vitro osteoblast responses to cpTi and Ti-6Al-4V alloy
- Creators
- John KellerClark StanfordRobert DraughnJames Wightman
- Resource Type
- Conference proceeding
- Publication Details
- Medical Applications of Titanium and Its Alloys: The Material and Biological Issues, ASTM STP 1272, pp.319-332
- DOI
- 10.1520/STP16088S
- ISSN
- 0066-0558
- Publisher
- American Society for Testing and Materials
- Language
- English
- Date published
- 01/01/1996
- Academic Unit
- Roy J. Carver Department of Biomedical Engineering; Dentistry Administration; Prosthodontics; Orthopedics and Rehabilitation; Craniofacial Anomalies Research Center; Oral and Maxillofacial Surgery
- Record Identifier
- 9984367642902771
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