Conference proceeding
Incorporation of learned shape priors into a graph-theoretic approach with application to the 3D segmentation of intraretinal surfaces in SD-OCT volumes of mice
Progress in Biomedical Optics and Imaging - Proceedings of SPIE, Vol.9038, pp.90380D-90380D-10
03/13/2014
DOI: 10.1117/12.2043203
Abstract
Spectral-domain optical coherence tomography (SD-OCT) finds widespread use clinically for the detection and management of ocular diseases. This non-invasive imaging modality has also begun to find frequent use in research studies involving animals such as mice. Numerous approaches have been proposed for the segmentation of retinal surfaces in SD-OCT images obtained from human subjects; however, the segmentation of retinal surfaces in mice scans is not as well-studied. In this work, we describe a graph-theoretic segmentation approach for the simultaneous segmentation of 10 retinal surfaces in SD-OCT scans of mice that incorporates learned shape priors. We compared the method to a baseline approach that did not incorporate learned shape priors and observed that the overall unsigned border position errors reduced from 3.58 +/- 1.33 μm to 3.20 +/- 0.56 μm.
Details
- Title: Subtitle
- Incorporation of learned shape priors into a graph-theoretic approach with application to the 3D segmentation of intraretinal surfaces in SD-OCT volumes of mice
- Creators
- Bhavna J Antony - The Univ. of Iowa (United States)Qi Song - GE Global Research (United States)Michael D Abràmoff - The Univ. of Iowa (United States)Eliott Sohn - The Univ. of Iowa (United States)Xiaodong Wu - The Univ. of Iowa (United States)Mona K Garvin - Iowa City VA Health Care System (United States)
- Contributors
- Robert C Molthen (Editor) - Medical College of Wisconsin (United States)John B Weaver (Editor) - Dartmouth Hitchcock Medical Ctr. (United States)
- Resource Type
- Conference proceeding
- Publication Details
- Progress in Biomedical Optics and Imaging - Proceedings of SPIE, Vol.9038, pp.90380D-90380D-10
- Publisher
- SPIE
- DOI
- 10.1117/12.2043203
- ISSN
- 1605-7422
- Language
- English
- Date published
- 03/13/2014
- Academic Unit
- Ophthalmology and Visual Sciences; Radiation Oncology; Roy J. Carver Department of Biomedical Engineering; Electrical and Computer Engineering; Fraternal Order of Eagles Diabetes Research Center
- Record Identifier
- 9984060741102771
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